FRS2 antibody

Volume: 100 µg Purification: Immunogen affinity purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Rabbit Clonality: polyclonal Clone ID: Isotype: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background: Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1. Immunogen: fibroblast growth factor receptor substrate 2 Synonyms: FGFR signaling adaptor SNT, FGFR substrate 2, FRS2, FRS2A, FRS2alpha, SNT, SNT 1, SNT1 Observed MW: 60 kDa Uniprot ID: Q8WU20 Reactivity: Human, Mouse, Rat Tested Application: ELISA, IHC, WB, IF Recommended dilution: WB: 1: 500-1: 5000; IHC: 1: 20-1: 200; IF: 1: 10-1: 100 Gene ID: 10818 Research Area: Signal Transduction